We’re building the safety layer for clinical AI
For more than two decades, MDCalc has helped clinicians bring evidence-based medicine to the bedside — trust we earned slowly. As medicine enters the AI era, we’re building the infrastructure, governance, and safeguards that enable clinicians and health systems to adopt these tools without surrendering that standard.
Our Purpose
Every clinician knows what it means to cross-cover. While they’re away, or busy, or unavailable, we take on another doctor’s patients as if they were our own, knowing that later, they’ll do the same for us. That trust is earned through shared accountability. That’s the standard we hold AI to: it should support the clinician, not replace their judgment. CrossCover adds an independent layer of scrutiny around clinical AI, while keeping physicians in control of the final call.
Our purpose is simple — help medicine adopt AI safely, transparently, and responsibly.
We Put Physicians in Control
Clinical judgment cannot be outsourced. CrossCover is designed to surface the information physicians should see while keeping the final clinical decision where it belongs.
Safety Is in Our DNA
Safety isn’t a feature — it’s the foundation. Every decision answers to the principles that have shaped MDCalc for over twenty years: clinical rigor, transparency, accuracy, and physician trust.
Clinical AI Needs Responsible Governance
Most AI wasn’t built for healthcare. Clinical environments require oversight, accountability, and clear standards for how AI is used. CrossCover exists to provide the oversight, accountability, and governance layer that modern clinical AI requires.
We Believe Safety Is a Team Sport
No single company will determine the future of clinical AI. We’re building CrossCover to work alongside the models, platforms, publishers, societies, and researchers shaping the field.
A letter from our founders
Medicine runs on trust. When AI enters clinical workflows, that trust depends on more than a good model. It depends on safeguards physicians can see, understand, and act on.
We started CrossCover because we believe the people using AI every day should be the ones setting the standard for how it is used.
Drs. Joe Habboushe, Graham Walker & Shazia Siddique
Built and tested by clinicians, for clinical practice
CrossCover is built by a team of physicians, healthcare operators, engineers, and product leaders with deep experience in clinical decision support and evidence-based medicine.
Graham Walker, MD
Co-Founder of CrossCover & MDCalc, Emergency Physician
Joseph Habboushe, MD, MBA
Co-Founder & CEO of MDCalc, Emergency Medicine
Shazia Siddique, MD, MSHP
Chief Medical Officer of MDCalc, Gastroenterology and Clinical Epidemiology
Alex J. Goodell, MD, MS
Clinical AI Lead of CrossCover & MDCalc, Anesthesiology and Internal Medicine
Sarah Gebauer, MD
Senior AI Advisor, Anesthesiology and Palliative Medicine
Our Collaboration
CrossCover is designed to work across the clinical AI ecosystem. We collaborate with AI companies, health systems, clinical organizations, medical journals, academic institutions, and nonprofit stakeholders shaping the future of clinical AI.
Founded in 2012 by doctors, for doctors, AMBOSS consists of over 100 staff physicians working alongside engineers and designers with one goal: optimizing how medical evidence reaches busy clinicians. AMBOSS Clinical AI is ranked #1 in safety and completeness in both Stanford-Harvard NOHARM studies.
Vera is the leading medical search engine that finds, grades and cites the best available evidence in seconds, used by more than 800,000 clinicians. When you type a question, Vera instantly searches more than 60 million peer-reviewed papers, medical guidelines, drug references, and real-world care pathways.
ECRI is an independent, nonprofit organization improving the safety, quality, and cost-effectiveness of care across all healthcare settings.
The American College of Physicians is the largest medical specialty organization in the United States with members in more than 172 countries worldwide.